The "Systems-based responses to cancer therapeutics" Integrative Cancer Biology Program is one of six NIH/NCI funded ICBP centers in the US.

The goal of this program is to promote the analysis of cancer as a
complex biological system, by supporting the development of reliably
predictive in silico or computational models of cancer initiation and
progression that can ultimately lead to the development of improved
cancer interventions. The overall thrust of this program is the
integration of experimental and computational approaches towards the understanding of cancer biology. The initiative encourages the
emergence of integrative cancer biology as a distinct field.

The National Cancer Institute (NCI) recognizes that biomedical research is entering an era in which computational approaches will be increasingly used to deepen our understanding of biological behavior. Building upon mechanistic
descriptions of individual biological constituents, there will be an increasing emphasis on concepts and methods that target systems and their integrated behavior and increasing dependence of cancer biologists on expertise from computational sciences as well as other fields of science that consider complex systems. This initiative is intended to facilitate the establishment of research programs in integrative cancer biology, which bring together cancer biologists and scientists from fields such as mathematics, physics, information
technology, imaging sciences, and computer science to work on a common
cancer biology problem.

The RFA of this NIH/NCI initiative is available here .

More information about NIH/NCI ICBP available here .